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2-Aminopurine Allows Interspecies Recombination by a Reversible Inactivation of the Escherichia coli Mismatch Repair System

2-Aminopurine treatment of Escherichia coli induces a reversible phenotype of DNA mismatch repair deficiency. This transient phenotype results in a 300-fold increase in the frequency of interspecies conjugational recombination with a Salmonella enterica serovar Typhimurium Hfr donor. This method can...

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Detalhes bibliográficos
Main Authors: Matic, Ivan, Babic, Ana, Radman, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC142871/
https://ncbi.nlm.nih.gov/pubmed/12562818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.4.1459-1461.2003
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