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Epoprostenol (prostacyclin, PGI2) binding and activation of adenylate cyclase in platelets of diabetic and control subjects.

1 The binding of epoprostenol (prostacyclin, PGI2) to isolated fractured human platelets has been studied using tritiated PGI2. 2 High and low affinity binding sites for PGI2 have been identified (Kd values = 16 and 382 nM). 3 Analysis of the prostacyclin-dependent activation of adenylate cyclase su...

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Hlavní autoři: Shepherd, G L, Lewis, P J, Blair, I A, de Mey, C, MacDermot, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427836/
https://ncbi.nlm.nih.gov/pubmed/6342639
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