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Evidence for a dual action of sulphinpyrazone on drug metabolism in man: theophylline-sulphinpyrazone interaction.

The effects of sulphinpyrazone administration on the metabolic and renal clearances of theophylline in man were investigated. Sulphinpyrazone increased total plasma theophylline clearance by 22%. This was the sum of increases in metabolic clearances by 3-demethylation (32%), 1-demethylation (30%) an...

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Sonraí Bibleagrafaíochta
Main Authors: Birkett, D J, Miners, J O, Attwood, J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1983
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427728/
https://ncbi.nlm.nih.gov/pubmed/6860533
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