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Effects of dazoxiben, an inhibitor of thromboxane synthetase, on forearm vasoconstriction in response to cold stimulation, and on human blood vessel prostacyclin production

1 In healthy male volunteers dazoxiben (UK 37248), an inhibitor of thromboxane synthetase, abolished the arterial and venous vasoconstriction produced in the forearm by cold stimulation. 2 Aspirin alone had no effect on this vasoconstriction but negated the effect of dazoxiben. 3 In vitro dazoxiben...

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Bibliographic Details
Main Authors: Cowley, A. J., Jones, E. W., Hanley, S. P.
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427702/
https://ncbi.nlm.nih.gov/pubmed/6337600
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