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Cardiovascular effects of withdrawal of some centrally acting antihypertensive drugs in the rat

1 We have studied on the cardiovascular effects appearing after termination of 12 day continuous infusions with clonidine (500 μg/kg/day), guanfacine (10 mg/kg/day), azepexole (B-HT 933, 10 and 60 mg/kg/day) and α-methyldopa (200 mg/kg/day) in conscious spontaneously hypertensive rats. 2 The infusio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Thoolen, M. J. M. C., Timmermans, P. B. M. W. M., Van Zwieten, P. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427668/
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