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Altered disposition and availability of cimetidine in liver cirrhotic patients.

1 The pharmacokinetics and bioavailability of cimetidine were studied after 200 mg oral and intravenous doses in 14 patients with liver cirrhosis, and results were compared to a control group of 12 ulcer patients. 2 In cirrhotic patients, the volume of the central compartment (0.41 +/- 0.06 v 0.19 +...

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Autors principals: Gugler, R, Müller-Liebenau, B, Somogyi, A
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427622/
https://ncbi.nlm.nih.gov/pubmed/7126415
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