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Enalapril maleate and a lysine analogue (MK-521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system.

1 Two single doses of 10 mg each of the converting enzyme inhibitor enalapril maleate or MK-421 and of its lysine analogue (MK-521) were administered p.o. to twelve male volunteers. 2 The active diacid metabolite of MK-421 and the lysine analogue were determined by radioimmunoassay and MK-421 by the...

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Detalhes bibliográficos
Main Authors: Biollaz, J, Schelling, J L, Jacot Des Combes, B, Brunner, D B, Desponds, G, Brunner, H R, Ulm, E H, Hichens, M, Gomez, H J
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1427615/
https://ncbi.nlm.nih.gov/pubmed/6289859
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