Protease-Stable Polycationic Photosensitizer Conjugates between Polyethyleneimine and Chlorin(e6) for Broad-Spectrum Antimicrobial Photoinactivation

We previously showed that covalent conjugates between poly-l-lysine and chlorin(e6) were efficient photosensitizers (PS) of both gram-positive and gram-negative bacteria. The polycationic molecular constructs increased binding and penetration of the PS into impermeable gram-negative cells. We have n...

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Detalhes bibliográficos
Main Authors: Tegos, George P., Anbe, Masahiro, Yang, Changming, Demidova, Tatiana N., Satti, Minahil, Mroz, Pawel, Janjua, Sumbul, Gad, Faten, Hamblin, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426948/
https://ncbi.nlm.nih.gov/pubmed/16569858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1402-1410.2006
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