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Overexpression of tnaC of Escherichia coli Inhibits Growth by Depleting tRNA(2)(Pro) Availability

Transcription of the tryptophanase (tna) operon of Escherichia coli is regulated by catabolite repression and tryptophan-induced transcription antitermination. Induction results from ribosome stalling after translation of tnaC, the coding region for a 24-residue leader peptide. The last sense codon...

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Autori principali: Gong, Ming, Gong, Feng, Yanofsky, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426567/
https://ncbi.nlm.nih.gov/pubmed/16484200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.5.1892-1898.2006
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