Roles of Cellular Respiration, CgCDR1, and CgCDR2 in Candida glabrata Resistance to Histatin 5

Histatin 5, a human salivary protein with broad-spectrum antifungal activity, is remarkably ineffective against Candida glabrata. Fluconazole resistance in this fungus is due in most cases to upregulation of CgCDR efflux pumps. We investigated whether the distinct resistance of C. glabrata to histat...

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Detaylı Bibliyografya
Asıl Yazarlar: Helmerhorst, Eva J., Venuleo, Caterina, Sanglard, Dominique, Oppenheim, Frank G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426449/
https://ncbi.nlm.nih.gov/pubmed/16495279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.1100-1103.2006
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