Lack of Evidence for In Vivo Transformation of Zidovudine Triphosphate to Stavudine Triphosphate in Human Immunodeficiency Virus-Infected Patients

The in vivo and in vitro determination of significant intracellular stavudine (d4T) triphosphate (d4TTP) concentrations in human immunodeficiency virus (HIV)-infected subjects and NS-1 cells treated with zidovudine (ZDV) has recently been reported. This study was conducted to corroborate these findi...

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Autores principales: Meléndez, Margarita, Blanco, Raúl, Delgado, Wilfredo, García, Rosario, Santana, Jorge, García, Hermes, Rosario, Osvaldo, Rodríguez, José F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426443/
https://ncbi.nlm.nih.gov/pubmed/16495240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.835-840.2006
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