In Vitro Characterization of the Anti-Hepatitis B Virus Activity and Cross-Resistance Profile of 2′,3′-Dideoxy-3′-Fluoroguanosine

The fluorinated guanosine analog 2′,3′-dideoxy-3′-fluoroguanosine (FLG) was shown to inhibit wild-type (wt) hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV. Experiments performed in the duck model of HBV infection also showed its in vivo antiviral activit...

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Detalhes bibliográficos
Main Authors: Jacquard, A.-C., Brunelle, M.-N., Pichoud, C., Durantel, D., Carrouée-Durantel, S., Trepo, C., Zoulim, F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426422/
https://ncbi.nlm.nih.gov/pubmed/16495257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.955-961.2006
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