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L-Asparaginase and in vitro lymphocyte blastogenesis: Cell membrane alteration as possible mechanism of inhibitory effect

Lymphocytes which were incubated with Erwinia carotovara L-asparaginase for only 1 hour were found to be markedly non-responsive to soluble antigens and moderately non-responsive to allogeneic cells or phytohaemagglutinin. When lymphocytes were exposed to antigen first, the inhibitory effect of L-as...

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Detalhes bibliográficos
Main Authors: Han, T., Ohnuma, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1423103/
https://ncbi.nlm.nih.gov/pubmed/4843755
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