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Effector activating determinants on IgG: II. Differentiation of the combining sites for C1q from those for cytotoxic K cells and neutrophils by plasmin digestion of rabbit IgG

Plasmin digestion of rabbit IgG after pretreatment at low pH yields a fragment (Facb) which has lost the C(H)3 domain. A study of the biological activity of this fragment is described and the following conclusions are drawn: (1) Facb possesses the same antigen-combining capacity as the whole antibod...

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Detalhes bibliográficos
Main Authors: MacLennan, I. C. M., Connell, G. E., Gotch, Frances M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1423080/
https://ncbi.nlm.nih.gov/pubmed/4277464
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