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Lack of ceramide generation and altered sphingolipid composition are associated with drug resistance in human ovarian carcinoma cells
PTX (Paclitaxel®) is an antimitotic agent used in the treatment of a number of major solid tumours, particularly in breast and ovarian cancer. This study was undertaken to gain insight into the molecular alterations producing PTX resistance in ovarian cancer. PTX treatment is able to induce apoptosi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422777/ https://ncbi.nlm.nih.gov/pubmed/16356169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051184 |
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