A murine cytomegalovirus-neutralizing monoclonal antibody exhibits autoreactivity and induces tissue damage in vivo.

The autoreactivity of murine cytomegalovirus (MCMV)-neutralizing monoclonal antibody (mAb) AC1 was examined in vitro and in vivo. Both mAb AC1 and a human antiserum reactive with U1-small nuclear ribonucleoprotein (U1-snRNP) stained uninfected mouse embryo fibroblasts (MEF) in a speckled nuclear pat...

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Bibliographic Details
Main Authors: Chapman, A J, Farrell, H E, Thomas, J A, Papadimitriou, J M, Garlepp, M J, Scalzo, A A, Shellam, G R
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422350/
https://ncbi.nlm.nih.gov/pubmed/7515848
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