Reduction of spontaneous autoimmune diabetes in diabetes-prone BB rats with the novel immunosuppressant fusidic acid. Effect on T-cell proliferation and production of interferon-gamma.

Diabetes-prone (DP) BB rats spontaneously develop a hyperglycaemic condition which closely resembles human insulin-dependent diabetes mellitus (IDDM), both in terms of clinical and histological features. The incidence of IDDM was significantly reduced when these animals were treated with 2 or 4 mg f...

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Autors principals: Nicoletti, F, Di Marco, R, Morrone, S, Zaccone, P, Lembo, D, Grasso, S, Santoni, A, Meroni, P L, Bendtzen, K
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422331/
https://ncbi.nlm.nih.gov/pubmed/8157281
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