Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta.

BALB/c mice injected intraperitoneally with bacterial lipopolysaccharide (LPS) developed lethal septic shock. This was accompanied by significantly elevated concentrations of nitrite and nitrate in the plasma and expression of high levels of nitric oxide (NO) synthase activity in the lungs, heart, s...

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Hauptverfasser: Cunha, F Q, Assreuy, J, Moss, D W, Rees, D, Leal, L M, Moncada, S, Carrier, M, O'Donnell, C A, Liew, F Y
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422329/
https://ncbi.nlm.nih.gov/pubmed/7512527
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