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Developmental regulation of bcl-2 expression in the thymus.

An important factor in shaping the T-cell receptor (TcR) repertoire during thymocyte development is the susceptibility of double-positive (CD4+ CD8+) thymocytes to induction of apoptosis (negative selection) when the TcR is engaged by 'self'-antigens. Recent evidence has suggested that thi...

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Detalhes bibliográficos
Principais autores: Moore, N C, Anderson, G, Williams, G T, Owen, J J, Jenkinson, E J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422275/
https://ncbi.nlm.nih.gov/pubmed/8132207
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