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Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity.

The superantigen Staphylococcal enterotoxin A (SEA) conjugated to tumour-specific monoclonal antibodies (mAb) directs T cells to lyse tumour cells in the absence of major histocompatibility complex (MHC) class II. In contrast, the conjugate bound to MHC class II-negative tumour cells did not activat...

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Bibliografische gegevens
Hoofdauteurs: Lando, P A, Dohlsten, M, Hedlund, G, Brodin, T, Sansom, D, Kalland, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422194/
https://ncbi.nlm.nih.gov/pubmed/7505257
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