Anti-idiotypic immunization provides protection against lethal endotoxaemia in BALB/c mice.

Against lipid A (the conserved moiety of lipopolysaccharides from Gram-negative bacteria) neutralizing IgM monoclonal antibodies (mAb) 8-2 and 26-20 anti-idiotypic (Ab2) mAb were produced: Ab2 mAb KM-04 (IgG1) against mAb 8-2, and Ab2 mAb PW-1 (IgG2a) and PW-2 (IgG1) against mAb 26-20. The binding o...

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Autori principali: Cornelissen, J J, Maassen, K, van Emst, L, Weers, P M, Harmsen, M, Benaissa-Trouw, B J, Oosterlaken, T A, Kraaijeveld, C A, Verhoef, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421928/
https://ncbi.nlm.nih.gov/pubmed/8406595
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