Antibodies against phosphatidylinositol and inositol monophosphate specifically inhibit tumour necrosis factor induction by malaria exoantigens.

The active component of the exoantigens of malarial parasites which stimulates macrophages to secrete tumour necrosis factor (TNF) has been shown to depend upon a phospholipid, the activity of which was blocked by phosphatidylinositol (PI) and inositol monophosphate (IMP) in competitive inhibition s...

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Detalhes bibliográficos
Main Authors: Bate, C A, Taverne, J, Bootsma, H J, Mason, R C, Skalko, N, Gregoriadis, G, Playfair, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421753/
https://ncbi.nlm.nih.gov/pubmed/1628898
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