Inhibition of interleukin-1 beta mRNA expression and interleukin-1 alpha and beta secretion by a specific human recombinant interleukin-1 receptor antagonist in human peripheral blood mononuclear cells.

The transcription and translation of interleukin-1 (IL-1) may have a pleiotropic effect on the immune system and inflammatory diseases. Recently it has been reported that human monocytes not only produce IL-1 but also induce, with adherent IgG, the secretion of an IL-1 receptor antagonist (IL-1Ra),...

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Bibliographic Details
Main Authors: Conti, P, Feliciani, C, Barbacane, R C, Panara, M R, Reale, M, Placido, F C, Sauder, D N, Dempsey, R A, Amerio, P
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421632/
https://ncbi.nlm.nih.gov/pubmed/1427978
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