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A T-cell response to the anti-arthritic drug penicillamine in the mouse: requirements for generation of the drug-derived antigen.
Mice primed with the anit-arthritic drug D-penicillamine (DP) developed DP-specific T cells in the draining lymph nodes (DLN) which responded to drug-haptenated stimulator cells, but not to untreated control cells nor to free drug, in in vitro proliferation assays. The responder cells were CD4+ and...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1992
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421571/ https://ncbi.nlm.nih.gov/pubmed/1356912 |
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