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Modulation of JNK and p38 Stress Activated Protein Kinases In Isolated Islets of Langerhans: Insulin as an Autocrine Survival Signal
OBJECTIVE: The objective of this study was to determine the effects of islet isolation and cytokine exposure on e-JUN NH(2) terminal kinase (JNK) and p38 activation and whether insulin or the p38 inhibitor PD169316 could modify the response. SUMMARY BACKGROUND DATA: Islet transplantation exposes the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1421175/ https://ncbi.nlm.nih.gov/pubmed/11141234 |
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