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Angiotensin II Inhibitor DuP753 Attenuates Burn- and Endotoxin-Induced Gut Ischemia, Lipid Peroxidation, Mucosal Permeability, and Bacterial Translocation

OBJECTIVE: To investigate the role of angiotensin II as a mediator of burn- and sepsis-induced gut ischemia and reperfusion injury and to determine whether treatment with the angiotensin II inhibitor DuP753 can attenuate mucosal injury and bacterial translocation in a burn/endotoxemia porcine model....

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Main Authors: Tadros, Tamer, Traber, Daniel L., Heggers, J. P., Herndon, David N.
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421034/
https://ncbi.nlm.nih.gov/pubmed/10749619
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