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Sequential Accumulation of K-ras Mutations and p53 Overexpression in the Progression of Pancreatic Mucinous Cystic Neoplasms to Malignancy

OBJECTIVE: Pancreatic mucinous cystic neoplasms (MCNs) provide a spectrum of neoplastic changes ranging from benign to malignant. The authors have correlated K-ras mutations and p53 overexpression with the evolution of these tumors. METHODS: Areas of mild, moderate, or severe dysplasia were microdis...

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Detalhes bibliográficos
Main Authors: Jimenez, Ramon E., Warshaw, Andrew L., Z’graggen, Kaspar, Hartwig, Werner, Taylor, Dolores Z., Compton, Carolyn C., Fernández-del Castillo, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1420899/
https://ncbi.nlm.nih.gov/pubmed/10522720
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