Effect of matrine and carvedilol on collagen and MMPs activity of hypertrophy myocardium induced by pressure overload

Objective: To explore the effect and mechanism of matrine (Mt.) on myocardial interstitial fibrosis induced by pressure overload. Methods: Pressure overloaded myocardial hypertrophy was produced by banding of aorta abdominalis in 67 male Sprague-Dawley rats weighing (200±15) g. The rats were assigne...

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Bibliographic Details
Main Authors: Zhang, Ye-Jing, Xiang, Mei-Xiang, San, Jiang, Cheng, Gang, Wang, Shi-Sheng
Format: Artigo
Language:Inglês
Published: Zhejiang University Press 2006
Subjects:
Pharmaceutical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1419068/
https://ncbi.nlm.nih.gov/pubmed/16502514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.2006.B0245
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