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Contribution of Hemagglutinin/Protease and Motility to the Pathogenesis of El Tor Biotype Cholera

Vibrio cholerae is a highly motile organism that secretes a Zn-dependent metalloprotease, hemagglutinin/protease (HapA). HapA has been shown to have mucinase activity and contribute to the reactogenicity of live vaccine candidates, but its role in cholera pathogenesis is not yet clear. The contribut...

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Autores principales: Silva, Anisia J., Leitch, Gordon J., Camilli, Andrew, Benitez, Jorge A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418906/
https://ncbi.nlm.nih.gov/pubmed/16552036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2072-2079.2006
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