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Planar cell polarity signalling couples cell division and morphogenesis during neurulation

Environmental and genetic aberrations lead to neural tube closure defects (NTDs) in 1 in every 1000 births1. Mouse and frog models for these birth defects have suggested that Van Gogh-like 2 (Vangl2, also known as Strabismus) and other components of planar cell polarity (PCP) signalling control neur...

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Autors principals: Ciruna, Brian, Jenny, Andreas, Lee, Diana, Mlodzik, Marek, Schier, Alexander F.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1417047/
https://ncbi.nlm.nih.gov/pubmed/16407953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04375
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