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Splicing Speckles Are Not Reservoirs of RNA Polymerase II, but Contain an Inactive Form, Phosphorylated on Serine(2) Residues of the C-Terminal Domain

“Splicing speckles” are major nuclear domains rich in components of the splicing machinery and polyA(+) RNA. Although speckles contain little detectable transcriptional activity, they are found preferentially associated with specific mRNA-coding genes and gene-rich R bands, and they accumulate some...

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Detalhes bibliográficos
Principais autores: Xie, Sheila Q., Martin, Sonya, Guillot, Pascale V., Bentley, David L., Pombo, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415300/
https://ncbi.nlm.nih.gov/pubmed/16467386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0726
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