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Soluble TNF receptor production by activated T lymphocytes: differential effects of acute and chronic exposure to TNF.

Soluble tumour necrosis factor receptors (sTNF-R) are up-regulated at sites of chronic inflammation such as rheumatoid synovial joints. The p75 sTNF-R is the more abundant, suggesting an important role for this TNF inhibitor in regulating TNF bioactivity in vivo. As the precise cellular source of th...

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Détails bibliographiques
Auteurs principaux: Cope, A P, Aderka, D, Wallach, D, Kahan, M, Chu, N R, Brennan, F M, Feldmann, M
Format: Artigo
Langue:Inglês
Publié: 1995
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1415193/
https://ncbi.nlm.nih.gov/pubmed/7890302
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