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Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation

We explored the role of antigen valency in B cell receptor (BCR) activation and rearrangement of intracellular MHC class II compartments as factors that contribute to the efficacy of antigen presentation. Using primary B cells that express a hen egg lysozyme (HEL)-specific BCR, we found that oligome...

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Detalhes bibliográficos
Main Authors: Kim, You-Me, Pan, Jennifer Yi-Jiun, Korbel, Gregory A., Peperzak, Victor, Boes, Marianne, Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413933/
https://ncbi.nlm.nih.gov/pubmed/16492756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511315103
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