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Evolutionary fate of retroposed gene copies in the human genome

Given that retroposed copies of genes are presumed to lack the regulatory elements required for their expression, retroposition has long been considered a mechanism without functional relevance. However, through an in silico assay for transcriptional activity, we identify here >1,000 transcribed...

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Détails bibliographiques
Auteurs principaux: Vinckenbosch, Nicolas, Dupanloup, Isabelle, Kaessmann, Henrik
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413932/
https://ncbi.nlm.nih.gov/pubmed/16492757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511307103
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