Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion

Although leukocytes of the innate immune system, including eosinophils, contain within their granules preformed stores of cytokines available for selective and rapid release, little is known about the mechanisms governing the mobilization and secretion of these cytokines. Here we show that a cytokin...

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Bibliographic Details
Main Authors: Spencer, Lisa A., Melo, Rossana C. N., Perez, Sandra A. C., Bafford, Staci P., Dvorak, Ann M., Weller, Peter F.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413889/
https://ncbi.nlm.nih.gov/pubmed/16492782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508946103
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