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Identification of a domain in Yersinia virulence factor YadA that is crucial for extracellular matrix-specific cell adhesion and uptake

For many pathogens, cell adhesion factors are critical virulence determinants. Enteropathogenic Yersinia species express the afimbrial adhesin YadA, the prototype of a class of homotrimeric outer membrane adhesins, which mediates adherence to host cells by binding to extracellular matrix components....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heise, Tanja, Dersch, Petra
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413876/
https://ncbi.nlm.nih.gov/pubmed/16488979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507749103
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