Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence

The opportunistic pathogen Pseudomonas aeruginosa is responsible for systemic infections in immunocompromised individuals and chronic respiratory disease in patients with cystic fibrosis. Cyclic nucleotides are known to play a variety of roles in the regulation of virulence-related factors in pathog...

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Bibliographic Details
Main Authors: Kulesekara, Hemantha, Lee, Vincent, Brencic, Anja, Liberati, Nicole, Urbach, Jonathan, Miyata, Sachiko, Lee, Daniel G., Neely, Alice N., Hyodo, Mamoru, Hayakawa, Yoshihiro, Ausubel, Frederick M., Lory, Stephen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413825/
https://ncbi.nlm.nih.gov/pubmed/16477007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511090103
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