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Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence

The opportunistic pathogen Pseudomonas aeruginosa is responsible for systemic infections in immunocompromised individuals and chronic respiratory disease in patients with cystic fibrosis. Cyclic nucleotides are known to play a variety of roles in the regulation of virulence-related factors in pathog...

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Main Authors: Kulesekara, Hemantha, Lee, Vincent, Brencic, Anja, Liberati, Nicole, Urbach, Jonathan, Miyata, Sachiko, Lee, Daniel G., Neely, Alice N., Hyodo, Mamoru, Hayakawa, Yoshihiro, Ausubel, Frederick M., Lory, Stephen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413825/
https://ncbi.nlm.nih.gov/pubmed/16477007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511090103
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