Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells

Tumor cells have the capacity to proliferate indefinitely that is qualified as replicative immortality. This ability contrasts with the intrinsic control of the number of cell divisions in human somatic tissues by a mechanism called replicative senescence. Replicative immortality is acquired by inac...

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Bibliographic Details
Main Authors: Ozturk, Nuri, Erdal, Esra, Mumcuoglu, Mine, Akcali, Kamil C., Yalcin, Ozden, Senturk, Serif, Arslan-Ergul, Ayca, Gur, Bala, Yulug, Isik, Cetin-Atalay, Rengul, Yakicier, Cengiz, Yagci, Tamer, Tez, Mesut, Ozturk, Mehmet
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413736/
https://ncbi.nlm.nih.gov/pubmed/16461895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510877103
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