Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma

Although mantle cell lymphoma (MCL) frequently harbors inactivated ataxia telangiectasia mutated (ATM) and p53 alleles, little is known about the molecular phenotypes caused by these genetic changes. We identified point mutations and genomic deletions in these genes in a series of cyclin D1-positive...

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Auteurs principaux: Greiner, Timothy C., Dasgupta, Chiranjib, Ho, Vincent V., Weisenburger, Dennis D., Smith, Lynette M., Lynch, James C., Vose, Julie M., Fu, Kai, Armitage, James O., Braziel, Rita M., Campo, Elias, Delabie, Jan, Gascoyne, Randy D., Jaffe, Elaine S., Muller-Hermelink, Hans K., Ott, German, Rosenwald, Andreas, Staudt, Louis M., Im, Michael Y., Karaman, Mazen W., Pike, Brian L., Chan, Wing C., Hacia, Joseph G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413716/
https://ncbi.nlm.nih.gov/pubmed/16461462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510441103
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