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Smooth muscle of telokin-deficient mice exhibits increased sensitivity to Ca(2+) and decreased cGMP-induced relaxation
Cyclic nucleotides can relax smooth muscle without a change in [Ca(2+)](i), a phenomenon termed Ca(2+) desensitization, contributing to vasodilation, gastrointestinal motility, and airway resistance. The physiological importance of telokin, a 17-kDa smooth muscle-specific protein and target for cycl...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413704/ https://ncbi.nlm.nih.gov/pubmed/16461919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508566103 |
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