Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

Age-related accumulation of cellular damage and death has been linked to oxidative stress. Calorie restriction (CR) is the most robust, nongenetic intervention that increases lifespan and reduces the rate of aging in a variety of species. Mechanisms responsible for the antiaging effects of CR remain...

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Main Authors: López-Lluch, G., Hunt, N., Jones, B., Zhu, M., Jamieson, H., Hilmer, S., Cascajo, M. V., Allard, J., Ingram, D. K., Navas, P., de Cabo, R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413655/
https://ncbi.nlm.nih.gov/pubmed/16446459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510452103
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