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Two Di-Leucine Motifs Regulate Trafficking of Mucolipin-1 to Lysosomes
Mutations in the mucolipin-1 gene have been linked to mucolipidosis type IV, a lysosomal storage disorder characterized by severe neurological and ophthalmologic abnormalities. Mucolipin-1 is a membrane protein containing six putative transmembrane domains with both its N- and C-termini localized fa...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Publishing Ltd
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413585/ https://ncbi.nlm.nih.gov/pubmed/16497227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2006.00387.x |
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