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Determinants of serum antipyrine half-lives in patients with liver disease
Antipyrine has been used as a model drug to investigate the effects of liver disease on drug metabolism in man. A prolongation in antipyrine half-life (T½) was found in patients with liver disease, patients with chronic liver disease showing a greater increase than those with acute, reversible patho...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1973
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1412804/ https://ncbi.nlm.nih.gov/pubmed/4729926 |
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