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Formation of a Tissue-Specific Histone Acetylation Pattern by the Hematopoietic Transcription Factor GATA-1

One function of lineage-restricted transcription factors may be to control the formation of tissue-specific chromatin domains. In erythroid cells, the β-globin gene cluster undergoes developmentally regulated hyperacetylation of histones at the active globin genes and the locus control region (LCR)....

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Autores principales: Letting, Danielle L., Rakowski, Carrie, Weiss, Mitchell J., Blobel, Gerd A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC141148/
https://ncbi.nlm.nih.gov/pubmed/12556492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1334-1340.2003
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