Small Maf Compound Mutants Display Central Nervous System Neuronal Degeneration, Aberrant Transcription, and Bach Protein Mislocalization Coincident with Myoclonus and Abnormal Startle Response

The small Maf proteins form heterodimers with CNC and Bach family proteins to elicit transcriptional responses from Maf recognition elements (MAREs). We previously reported germ line-targeted deficiencies in mafG plus mafK compound mutant mice. The most prominent mutant phenotype was a progressive m...

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הוצא לאור ב:	Mol Cell Biol
Principais autores:	Katsuoka, Fumiki, Motohashi, Hozumi, Tamagawa, Yuna, Kure, Shigeo, Igarashi, Kazuhiko, Engel, James Douglas, Yamamoto, Masayuki
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis 2003
נושאים:	Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12556477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.4.1163-1174.2003
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