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Molluscum Contagiosum Virus Interleukin-18 (IL-18) Binding Protein Is Secreted as a Full-Length Form That Binds Cell Surface Glycosaminoglycans through the C-Terminal Tail and a Furin-Cleaved Form with Only the IL-18 Binding Domain

Some poxviruses and their mammalian hosts encode homologous proteins that bind interleukin-18 (IL-18) with high affinity and inhibit IL-18-mediated immune responses. MC54L, the IL-18 binding protein of the human poxvirus that causes molluscum contagiosum, is unique in having a C-terminal tail of nea...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xiang, Yan, Moss, Bernard
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC141116/
https://ncbi.nlm.nih.gov/pubmed/12552001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2623-2630.2003
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