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Phosphatidylinositol 3-Kinase Regulates Human Immunodeficiency Virus Type 1 Replication following Viral Entry in Primary CD4(+) T Lymphocytes and Macrophages

Human immunodeficiency virus (HIV) gp120 induces multiple cellular signaling pathways, including the phosphatidylinositol 3-kinase (PI3-kinase) pathway. The role of the PI3-kinase pathway in HIV-1 replication is not understood. Here we examined whether HIV-1 gp120 upregulates the PI3-kinase pathway...

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Main Authors: François, Fleur, Klotman, Mary E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC141101/
https://ncbi.nlm.nih.gov/pubmed/12551992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2539-2549.2003
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