Mucosal Priming of Simian Immunodeficiency Virus-Specific Cytotoxic T-Lymphocyte Responses in Rhesus Macaques by the Salmonella Type III Secretion Antigen Delivery System

Nearly all human immunodeficiency virus (HIV) infections are acquired mucosally, and the gut-associated lymphoid tissues are important sites for early virus replication. Thus, vaccine strategies designed to prime virus-specific cytotoxic T lymphocyte (CTL) responses that home to mucosal compartments...

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Detalhes bibliográficos
Main Authors: Evans, David T., Chen, Li-Mei, Gillis, Jacqueline, Lin, Kuei-Chin, Harty, Brian, Mazzara, Gail P., Donis, Ruben O., Mansfield, Keith G., Lifson, Jeffrey D., Desrosiers, Ronald C., Galán, Jorge E., Johnson, R. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141091/
https://ncbi.nlm.nih.gov/pubmed/12551977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2400-2409.2003
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