Targeted Retroviral Infection of Tumor Cells by Receptor Cooperation

Retroviruses expressing two different receptor-binding domains linked by proline-rich spacers infect only cells expressing both retroviral receptors (Valsesia-Wittman et al., EMBO J. 6:1214-1223, 1997). Here we apply this receptor cooperation strategy to target human tumor cells by linking single-ch...

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Detalhes bibliográficos
Main Authors: Martin, Francisco, Chowdhury, Simon, Neil, Stuart J., Chester, Kerry A., Cosset, Francois-Loic, Collins, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141083/
https://ncbi.nlm.nih.gov/pubmed/12552017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2753-2756.2003
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