Estradiol alters only GAD(67) mRNA levels in ischemic rat brain with no consequent effects on GABA

The present study tested the hypothesis that estradiol reduces tissue infarction after middle cerebral artery occlusion (MCAO) in estradiol-deficient females by augmenting glutamic acid decarboxylase (GAD) expression and thus activity, leading to increases in γ-amino-butyric acid (GABA) tissue level...

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Main Authors: Joh, Hung-Dong, Searles, Robin V, Selmanoff, Michael, Alkayed, Nabil J, Koehler, Raymond C, Hurn, Patricia D, Murphy, Stephanie J
Format: Artigo
Jezik:Inglês
Izdano: 2006
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410818/
https://ncbi.nlm.nih.gov/pubmed/16094313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600211
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